Get smart. Sign up for our email newsletter. Sign Up. Support science journalism. Knowledge awaits. See Subscription Options Already a subscriber? Create Account See Subscription Options. Continue reading with a Scientific American subscription. In some cases, an individual will continue to take an opiate medication despite the presence of uncomfortable physical side effects like itchy skin. If this is the case, it might be because an opioid abuse disorder is present.
If you believe that you or someone you love has been struggling with an opiate abuse disorder, there are several telltale symptoms to keep an eye out for, including:. If you believe that you or someone you love has been struggling with an opiate abuse disorder, reaching out for professional help is always a necessity. Opiate addiction is a cunning, baffling, and powerful disease, and it is one that cannot be effectively overcome without help.
At Garden State Treatment Center we provide men and women of all ages throughout New Jersey and all surrounding areas with a comprehensive program of opiate addiction recovery. For more information on a recovery program, please feel free to reach out to us today.
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In the event of a medical emergency, call a doctor or immediately. Once that tentative picture was in place, we were able to use computational tools to create a more precise model of the site.
The computer modeling, performed by co-first author Joel Karpiak, a graduate student at the University California at San Francisco, tested 3.
The physical data combined with the computational models allowed the researchers to create a chemical probe designed to interact specifically with MRGRPX2. This new tool made it possible to gain a more precise understanding of this receptor's effects without the noise of other receptors. An opioid might activate the orphan receptor, but it might also activate other receptors that it interacts with. Imagine trying to recreate a musical score by listening to an orchestra perform a piece of music.
Understanding what triggers the itching response could help pharmacologists develop an antagonist for this receptor to reduce the itching side effect. In other cases, clinicians may want to induce histamine release, thereby boosting the immune response, as in the case of vaccine adjuvants, where an increased immune response may improve immunity.
These findings suggest there may be a way to do that selectively. The researchers will now move onto other orphans. She also emphasized that work like this would not be possible without the cooperation of a wide variety specialists.
And all of these specialists working together makes findings like these possible. Note: Content may be edited for style and length.
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